Glucuronolactone is a naturally occurring substance that is an important structural component of nearly all connective tissues. Glucuronolactone is also found in many plant gums. D-Glucuronolactone is a white solid odorless compound, soluble in hot and cold water. Glucuronolactone is metabolized to glucaric acid, xylitol, and L-xylulose, and humans may also be able to use glucuronolactone as a precursor for ascorbic acid synthesis. According to The Merck Index, it is also used as a detoxicant.