Magnesium Aluminium Silicate - magnesium aluminium silicates Suppliers, Magnesium Aluminium Silicate Manufacturers & muby Chemicals

Aluminium Magnesium Silicate

Synonyms: ---,


CAS Number: 12511-31-8 or 12174-11-7,


Molecular Weight: ----,


Chemical Formula: -----,


EINECS EC Number: 215-478-8 or 308-996-1,


FEMA: ----

Aluminium Magnesium Silicate BP Grade

Ph Eur
12511-31-8
Action and use: Excipient.

DEFINITION

Mixture of particles with colloidal particle size of montmorillonite and saponite, free from grit and non-swellable ore.
Content:
aluminium (Al; Ar 26.98): 95.0 per cent to 105.0 per cent of the value stated on  the label.
magnesium (Mg; Ar 24.30): 95.0 per cent to 105.0 per cent of the value stated  on the label.

CHARACTERS

Appearance: Almost white powder, granules or plates.
Solubility: Practically insoluble in water and in organic solvents.  It swells in water to produce a colloidal dispersion.

IDENTIFICATION

A. Fuse 1 g with 2 g of anhydrous sodium carbonate. Warm the residue with  water and filter. Acidify the filtrate with hydrochloric acid and evaporate to  dryness on a water-bath. 0.25 g of the residue gives the reaction of silicates.
B. Dissolve the remainder of the residue obtained in identification test A in a  mixture of 5 mL of dilute hydrochloric acid and 10 mL of water. Filter and add  ammonium chloride buffer solution pH 10.0. A white, gelatinous precipitate is  formed. Centrifuge and keep the supernatant for identification C. Dissolve the  remaining precipitate in dilute hydrochloric acid. The solution gives the reaction  of aluminium.
C. The supernatant liquid obtained after centrifugation in identification test B gives  the reaction of magnesium.

TESTS

pH: 9.0 to 10.0.
Arsenic: Maximum 3 ppm.
Lead: Maximum 15 ppm.
Loss on drying: Maximum 8.0 per cent, determined on 1.000 g by drying in an oven at 105C.
Microbial contamination:
TAMC: acceptance criterion 1000 CFU/g.
TYMC: acceptance criterion 100 CFU/g.
Absence of Escherichia coli.