Acetone BP Grade

Ph Eur monograph
C3H6O --- 58.08 --- 67-64-1

DEFINITION

Propanone.

CHARACTERS

Appearance: Volatile, clear, colourless liquid.
Solubility: Miscible with water and with ethanol (96 per cent). The vapour is flammable.

IDENTIFICATION

A. It complies with the test for relative density (see Tests).
B. To 1 ml, add 3 ml of dilute sodium hydroxide solution and 0.3 ml of a 25 g/l solution of sodium nitroprusside. An intense red colour is produced which becomes violet with the addition of 3.5 ml of acetic acid.
C. To 10 ml of a 0.1 per cent V/V solution of the substance to be examined in ethanol (50 per cent V/V), add 1 ml of a 10 g/l solution of nitrobenzaldehyde in ethanol (50 per cent V/V) and 0.5 ml of strong sodium hydroxide solution. Allow to stand for about 2 min and acidify with acetic acid. A greenish-blue colour is produced.

TESTS

Appearance of solution: To 10 ml add 10 ml of water. The solution is clear and colourless.
Acidity or alkalinity: To 5 ml add 5 ml of carbon dioxide-free water, 0.15 ml of PhPh solution and 0.5 ml of 0.01 M sodium hydroxide. The solution is pink. Add 0.7 ml of 0.01 M hydrochloric acid and 0.05 ml of methyl red solution. The solution is red or orange.
Relative density: 0.790 to 0.793.
Reducing substances: To 30 ml add 0.1 ml of 0.02 M potassium permanganate and allow to stand in the dark for 2 h. The mixture is not completely decolourised.
Related substances: Gas chromatography. To pass the test (0.05 per cent V/V).
Matter insoluble in water: Dilute 1.0 ml to 20 ml with water. The solution is clear.
Residue on evaporation: Maximum 50 ppm.
Water: Maximum 3 g/l, determined on 10.0 ml. Use 20 ml of anhydrous pyridine as solvent.

STORAGE

Protected from light.

IMPURITIES

Specified impurities A, B, C.
A. CH3-OH: methanol,
B. CH3-CHOH-CH3: propan-2-ol (isopropanol),
C. C6H6: benzene.

Acetone USP NF Grade

Acetone USP NF Grade
C3H6O 58.08
2-Propanone.
Acetone [67-64-1].

Acetone contains not less than 99.0 percent of C3H6O, calculated on the anhydrous basis.
[Caution—Acetone is very flammable. Do not use where it may be ignited. ]

Identification: The IR absorption spectrum of a thin film of it between potassium bromide plates exhibits a strong band at about 5.8 µm; a strong region of absorption between 6.8 and 7.5 µm, with maxima at about 7.0 and 7.3 µm; a strong maximum at about 8.2 µm; and weak maxima at about 9.2 and 11.0 µm.
Specific gravity:not more than 0.789.
Water:To pass the test (0.5%).
Nonvolatile residue: Evaporate 50 mL in a tared porcelain dish on a steam bath, and dry at 105C for 1 hour: the weight of the residue does not exceed 2 mg (0.004%).
Readily oxidizable substances: Mix 20 mL with 0.10 mL of 0.10 N potassium permanganate in a glass-stoppered bottle: the permanganate color of the mixture does not completely disappear within 15 minutes.

Acetone FCC Food Grade Grade

2-Propanone; Dimethyl Ketone
CH3COCH3
C3H6O Formula wt 58.08
CAS: [67-64-1]

DESCRIPTION

Acetone occurs as a clear, colorless, volatile liquid. It is miscible with water, with alcohol, with ether, with chloroform, and with most volatile oils.
Caution: Acetone is highly flammable.
Function: Extraction solvent.

REQUIREMENTS

Identification: Mix 0.1 mL of sample with 10 mL of water, add 5 mL of 1 N sodium hydroxide, warm, and add 5 mL of iodine. A yellow precipitate of iodoform forms.
Assay: Not less than 99.5% and not more than 100.5% of C3H6O, by weight.
Acidity: (as acetic acid) Not more than 0.002%.
Aldehydes (as formaldehyde): Not more than 0.002%.
Alkalinity (as ammonia): Not more than 10 mg/kg.
Distillation Range: Within a range of 1°, including 56.1°.
Lead: Not more than 1 mg/kg.
Methanol: Not more than 0.05%.
Nonvolatile Residue: Not more than 10 mg/kg.
Phenols: Passes test.
Refractive Index: Between 1.358 and 1.360.
Solubility in Water: Passes test.
Specific Gravity: Not greater than 0.7880 at 25°/25° (equivalent to 0.7930 at 20°/20°).
Substances Reducing Permanganate: Passes test.
Water: Not more than 0.5%.

Acetone Analytical Reagent Grade

2-Propanone
(CH3)2CO --- Formula Wt 58.08
CAS Number 67-64-1

REQUIREMENTS

Assay: 99.5% (CH3)2CO MAXIMUM ALLOWABLE
Color (APHA): 10
Residue after evaporation: 0.001%
Solubility in water: Passes test
Titrable acid: 0.0003 meq/g
Titrable base: 0.0006 meq/g
Aldehyde (as HCHO): 0.002%
Isopropyl alcohol: 0.05%
Methanol: 0.05%
Substances reducing permanganate: Passes test
Water: 0.5%