Carmellose

Synonyms: ...,

CAS Number: 9000-11-7,

Molecular Weight: ...,

Chemical Formula: ...,

EINECS EC Number: ...,

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Carmellose BP Grade

Ph Eur
Action and use: Excipient; bulk laxative.

DEFINITION

Polycarboxymethylether of cellulose.

CHARACTERS

Appearance: White or almost white powder, hygroscopic.
Solubility: Practically insoluble in anhydrous ethanol. It swells with water to form a suspension and becomes viscid in 1 M sodium hydroxide.

IDENTIFICATION

A. pH 3.5 to 5.0.
Suspend 1.0 g in 100 mL of water R.
B. Infrared absorption spectrophotometry

TESTS

Chlorides: Maximum 0.36 per cent.
Sulfates: Maximum 0.72 per cent.
Heavy metals: Maximum 20 ppm.
Loss on drying: Maximum 8.0 per cent, determined on 1.000 g by drying in an oven at 10C for 4 h.
Sulfated ash: Maximum 1.5 per cent, determined on 1.0 g.