Carbamide Peroxide USP Grade

CH6N2O3 -- 94.07
Urea compound with hydrogen peroxide (1:1) [124-43-6].
Carbamide Peroxide contains not less than 96.0 percent and not more than 102.0 percent of CH6N2O3.

Identification

A: Mix 1 mL of a solution (1 in 10) of it with 1 mL of nitric acid: a white, crystalline precipitate is formed.
B: A solution of it (1 in 10) responds to the tests for Peroxide.

Assay

Transfer about 100 mg of Carbamide Peroxide, accurately weighed, to a 500-mL iodine flask with the aid of 25 mL of water, add 5 mL of glacial acetic acid, and mix. Add 2 g of potassium iodide and 1 drop of ammonium molybdate, insert the stopper, and allow to stand in the dark for 10 minutes. Titrate the liberated iodine with 0.1 N sodium thiosulfate, adding 3 mL of starch as the endpoint is approached. Each mL of 0.1 N sodium thiosulfate is equivalent to 4.704 mg of CH 6N2O3.